Basic Information
VIS ID
TVIS10020247
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1191
End
2287
Orient
+
Integrated sequence
GCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAAT
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
GRCh37/hg19
Start
56661223/56195551 (Hg38)
End
56662271/56196599 (Hg38)
Orient
+
Fragile sites / regions
FRA1B
Nearest miRNA
hsa-mir-12136/Upstream/969828; hsa-mir-101-1/Downstream/3536628;
Nearest TSS
ENST00000473358/Upstream/1438; ENST00000635434/Downstream/18266;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/979516, chr1-CpG: 47/Downstream/280956
Upstream sequence
agacaggatcttgctctgttgcccaggctggagtgaagtggtacaattttggctcactacaacctctgcctcccaggttcaagcaattcttgtgtctcag
Downstream sequence
AACTGATGAGGCACTCCCTGGCAGGCCCTGATTATGCTGCATCCAGGAGACACCTAATCACATATATTTTCTTCCATCATACAGCCCAGCCAGGAGGCAG
Target sequence
CCCATATGACCGCTGTCGAGATTATTTCATCAGAGTTCTTGTTTTCAATGATCTCCCAAAGTTGGGAAtaacaactcccaaatttatatttccaaactacattttcttctgacttactgcctcatatatacaactgtcatcttcacatctttacttggatgtgctatatccatctcaagccaggtgtgtccaaaatggagattaacattttttcccacaaatttttcccttcaatgttctccacctccataaaga
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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