Basic Information
VIS ID
TVIS10020249
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
808
End
1904
Orient
+
Integrated sequence
TTCTTTTGTCTTTGGGTATACATTTGAACCCTAATAAAACCAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGGGTACTTTACCGCAGGAACATATTGTACAAAAACTCAAGCAATGTTTTCGAAAATTGCCTGTAAATAGACCTATTGATTGGAAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTAT
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
21729793/21375504 (Hg38)
End
21730841/21376552 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1286/Upstream/341232; hsa-let-7a-3/Downstream/276429;
Nearest TSS
ENST00000624155/Upstream/20941; ENST00000620804/Downstream/6822;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/13982, chr22-CpG: 210/Downstream/7134
Nearby gene
SUSD2P1(-3555) ; RIMBP3B(+8247) ;
Upstream sequence
GAGCCCAGACTCAGGTCACACAGACCTGCCCATAAGTCCCTGTGTGACCCTGGACAGTTTCCTTCTCTGGAGAGGAGAGTGCCAGGCTCCCTGGCTATGG
Downstream sequence
tagaggcgtgggccaccatgtccagcTTCACTTTTATTTCATAGGTGAGAAAGCTGGACCGGGAGAGGGTAGGAGCTTGGTGAGCCCATGCTGGGACACC
Target sequence
GGAGGATTCAGCGATGAGGCTTGTAAAGTGCAGATGGGAAGGGGCTGACCACTCGCTGCAGAGGCACATGAGCTAGGGAGCTGGGCCAGGGCCACCAGGGCAGGAAGCCAGCCCAGTAGGCCAGGGGGCCCCAGCCAGAGAGCTAGAAGCTCGCACCATACTGCCCTCCTGGCCCAGGAAGATGTGGACCAGCCAGGCAGGCTGCAGGGCCCAGGAAGAGCAGCACGGTCCCTCTCCAGGTATCCAGCCCCATCC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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