Basic Information
VIS ID
TVIS10020250
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
808
End
1904
Orient
+
Integrated sequence
TTCTTTTGTCTTTGGGTATACATTTGAACCCTAATAAAACCAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGGGTACTTTACCGCAGGAACATATTGTACAAAAACTCAAGCAATGTTTTCGAAAATTGCCTGTAAATAGACCTATTGATTGGAAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTAT
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
20468503/18618636 (Hg38)
End
20469551/18619684 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-3198-1/Upstream/637675; hsa-let-7a-3/Downstream/1344069;
Nearest TSS
ENST00000624155/Upstream/6717; ENST00000342888/Downstream/114230;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/7030, chr22-CpG: 112/Downstream/14076
Nearby gene
RIMBP3(-6717) ; SUSD2P2(+4703) ;
Upstream sequence
GACTGAAgaagacagaggcagacaggccagatgtggctgctgtccttagggaattgacagtccaTGATCTATGAGAATGAGCTGCAGACTGGGAGGCAGG
Downstream sequence
CTGGTGGCCCTGGCCCAGCTCCCCAGCTCATGTGCCTCTGCAGCGAGTGGTCAGCCCCTTCCCATCTGCACTTTACAAGCCTCATCGCTGAATCCTCCCC
Target sequence
TGTCCCAGCATGGGCTCACCAAGCTCCTACCCTCTCCCGGTCCAGCTTTCTCACCTATGAAATAAAAGTGAAgctggacatggtggcccacgcctctaatctcagcagtttgggaggccaaggtgggtggatcacttgagatcaggagattgagaccagcctggctaacatggtgaaaccccatctctactaaaaaacacaaaaattagccgggcgtggtggcagttgcctgtaatcccagctactcgggaggct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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