Basic Information
VIS ID
TVIS10020251
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
127
End
1223
Orient
+
Integrated sequence
TCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGCTATCGCTGGATGTGT
Host Sequence
Chromosome
chr7
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
99486535/99888912 (Hg38)
End
99487583/99889960 (Hg38)
Orient
+
Fragile sites / regions
FRA7F
Nearest miRNA
hsa-mir-10525/Upstream/479648; hsa-mir-10399/Downstream/203600;
Nearest TSS
ENST00000635602/Upstream/11855; ENST00000456499/Downstream/19638;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/271650, chr7-CpG: 76/Downstream/29019
Nearby gene
TRIM4(+1495) ;
Upstream sequence
GTCTTGTTCTCAGGTATAGCATTCCTCCTCAGCCcttcacaggattatttaagtatcaaaagctacaacataaagagagtacctggcacagtgtttgatg
Downstream sequence
ttccatctggcatttttctgtgtgtgtgtgggcatgagtgtgtgaacatatgcataagtttccttctttttataaggacaccagtcatattgggttagag
Target sequence
gggcaccattgagcactgagtgaaccagacccgtctgcaatcctggcacctccggaggccaaggctggcagatcactcgcggttaggagctggagaccagcccggccaacacagcgaaaccccgtctccaccaaaaaaatacgaaaaccaatcaggcgtggcggcgcgcgcctgcaatcgcaggcactcggcaggctgaggcaggagaatcaggcagggaggttgcagtgagccgagatggcagcagtacagtcc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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