VISDB Viral Integration Site DataBase

VIS ID

TVIS10020252

Fusion event

HBV-WRAP53 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1

End

1049

Orient

-

Integrated sequence

TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7592487/7689169 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-455-3p ; hsa-mir-106b-3p

Nearest miRNA

hsa-mir-1253/Upstream/464742; hsa-mir-10226/Downstream/398887;

Nearest TSS

Nearest CpG islands

chr17-CpG: 36/Target, None/Upstream, None/Downstream

Upstream sequence

gaggctgaggcaggagaatggcgtgaacccgggaggcggagcttgcagtgagccgagattgagccactgcaccccagcctgggcgacagagcgagactcc

Target sequence

AATAGTTATTATTAATACATGTTAAAAACATGGCTCAAACCAAAGAAAGCTTAATATTGTCCTCAGCACACAACAGTACCTATACAGTAGAATAAGAACCAAAGATTGTTTATACAAAAATTAATTCACTGCTGAAAAAGGCACTAACTGAGAAGCCGTAAAGTACAAGTATTTCCTACAGGGTACCTGCTATGTACAAGCTTCTGTCATTCTGTTTCAGAGAAGATGCTGAAATGAATACACATGAATGAAAGT