Basic Information
VIS ID
TVIS10020253
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
1092
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
GRCh37/hg19
Start
56712791/56247119 (Hg38)
End
56713839/56248167 (Hg38)
Orient
+
Fragile sites / regions
FRA1B
Nearest miRNA
hsa-mir-12136/Upstream/1021396; hsa-mir-101-1/Downstream/3485060;
Nearest TSS
ENST00000473358/Upstream/21966; ENST00000635434/Downstream/10404;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1031084, chr1-CpG: 47/Downstream/229388
Upstream sequence
tgacatccactgTCTTAGGCAAGCCTCAACCCTCCTAGGGAAACCAAAAGACAAATGGTTTCCCTGAGCTCCTCATCCTCCTTACCTTCTCTGTGTCAAT
Downstream sequence
attcttcccaaaaaaaggtattagaagtaaatgagtttaaccagcctgcaggatacaaaatcaataatccaaagatcaattacatatccatatgctagca
Target sequence
TTCAAAAACAaaagagttggataaggagtcagacaacccaggactcgcgtagcagctcccctagctcctctccttagctgtatattcttaggaaattcatttcatttctccaagcatccaattctttgtcaatactcacccaccccctcatagccattattgtctaatgatgctgtgaagctcagctgagctcatgaatgcaaaagcattctatacaccatgaaagactacacatatgaaaggAACTGCTTTGTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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