VISDB Viral Integration Site DataBase

VIS ID

TVIS10020262

Fusion event

HBV-PIGR integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1806

End

2902

Orient

+

Integrated sequence

CAGCACCATGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGC

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

207106317/206932972 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6720-5p ; hsa-mir-7703 ; hsa-mir-6512-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-4793-3p ; hsa-mir-4486 ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4743-5p ; hsa-mir-6089 ; hsa-mir-583 ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-3937 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-133a-3p ; hsa-mir-4713-5p ; hsa-mir-642a-5p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-4281 ; hsa-mir-7152-3p ; hsa-mir-1236-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-877-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-1224-3p ; hsa-mir-3620-3p ; hsa-mir-504-5p

Nearest miRNA

hsa-mir-101-1/Upstream/457060; hsa-mir-1182/Downstream/868880;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/22067, chr1-CpG: 38/Downstream/117772

Upstream sequence

gcagggtggggcatcacctcacccaggaagcacaagggatagggaactccctcctgtagccaagggaagccctgagggactgtgctgtgaggaatagtgc

Downstream sequence

AATCCTTCCTTACCTGCCGGAATCCACAGATGCTCTGCTCCCATCGGCTTGATCTCTTGTATCTGCCACCGCCTTTTCCTCTGCAAAAAGCCTGGGATCC

Target sequence

TGACTATGACCCAGGGGGATGGAAATGATCCGAGTCTCCTCCCCAGTCCCTTTTCCTGGGTAATCAGGACTTGGTAATCCCTGATCTTTGTCACTCTGGGACctttcaatgcacagcatctcctttggtcctcacatcagccccgtgaggtcctgattatcatccttgacttgagccatgaggaaactgaggcatggcataaggatggctcaatgtcacacagctcattagttatccaattagtccaagcccagg