VISDB Viral Integration Site DataBase

VIS ID

TVIS10020263

Fusion event

HBV-HSD17B4 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1805

End

2901

Orient

+

Integrated sequence

CCAGCACCATGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAG

Chromosome

chr5

Cytoband

q23.1

Reference genome

Start

End

118825387/119489692 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-484 ; hsa-mir-324-5p ; hsa-mir-142-3p

Nearest miRNA

hsa-mir-10397/Upstream/333928; hsa-mir-103a-1/Downstream/9607996;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/35911, chr5-CpG: 42/Downstream/974434

Upstream sequence

ataggagctttggccaggggcggtggctcacacctgtaattccagcactttggggcaccaaggtgagtggatcacctgaggtcagaggtttgagaccagg

Downstream sequence

TATTTTAAACCCTTGGCATAAGGCCTAATACATAGCACTCAACCACCAATTTTAATTATCAGTATAGCAGGAATTTAATCTTGTGTGATAGGTCaataaa

Target sequence

GGTAACATATGCAGTGGGAAATTAGTTCTTATACTTTGTGCACTCACCAGTGATGTCTTCAAGGTCTATTTCAATCATTATCTGCCTAccctggtggtctagtggttaggattcagcactctcaATCATTATTTGCCACTGTAATGGTCTAGGCTGTTTTGTGATTTTCTAGATTGTTGTTAATAGCTGGGAGAGTAGAATAATTTTGGGAATGAATGGTACCCAGATTTCTCATGTTAAATACAGTTTTGCTCA