Basic Information
VIS ID
TVIS10020266
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1195
End
2291
Orient
+
Integrated sequence
CCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCG
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
49076838/48683055 (Hg38)
End
49077886/48684103 (Hg38)
Orient
+
Fragile sites / regions
FRA12A
Nearest miRNA
hsa-mir-1244-3/Upstream/28525; hsa-let-7i/Downstream/87872;
Nearest TSS
ENST00000382841/Upstream/817; ENST00000548054/Downstream/11874;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/537, chr12-CpG: 66/Downstream/32169
Nearby gene
KANSL2(-803) ; CCNT1(+5403) ;
Upstream sequence
aacaaaagccaaaattgataaatgggagctaattaaactaaagagcttctgcacagcaaaagaaactatcatcagagtgaaaaggaaacctacagaatgg
Downstream sequence
CGAATCTGCAACCAAATGTAGTAATATCAAAAAGCAACATTAAAACTACTGTAGTGAACAATATGAAGAGACACAGGAATAGATGGGGAAGAAACAAAAG
Target sequence
taaagtcattgaatttttcaaagcaaccctaagaggtacaggttagtattatgtccattttacagataagaggactgaggaacagaatgggaccatagctattaaatgggaaaggaagacgaatttgaacccagCCCGCATTCTTTATCCCTTATTGCCTCTTATATAGTaaagagcattggactgagaataaggaaatatttgttctagtttagggctgcttctcataactgtgtgccctGTCTTTAAAATTCC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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