Basic Information
VIS ID
TVIS10020267
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1322
End
2418
Orient
+
Integrated sequence
TATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCG
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
82406499/82179375 (Hg38)
End
82407547/82180423 (Hg38)
Orient
+
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/2312792; hsa-mir-10b/Downstream/3603177;
Nearest TSS
ENST00000437798/Upstream/173675; ENST00000448431/Downstream/358288;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/711818, chr2-CpG: 27/Downstream/2110167
Upstream sequence
GCCAATTCAGGACAGTGTCAAACAGTTCAGGGGTTCTTTTGTTGCACACTATGTCACCAAAATTATTTCCTAAAAGGGCACAAAAGAATAGAGTGCATGG
Downstream sequence
aattgggcccttatatattacacaaaagtcaagtcaaaataggttactcttaaatgtaattcctgagattctaaatctccctaaagaaaacatggggtag
Target sequence
gtttctgttgtttaagattcccagtcttgggtattttgttatggcagaccaaGATAATACAAAAATTAATCTTGATGATTTGGAATAAGTGATTTGGAATCTGTAATAAAAACATAACAATTGTAATGCATTTATGTGTATGTGTTTGTGGAATACCAAATGGCATAAACACAATAAAAAATTGTTGAGGAAAATAATTAAAGTGGGGAAAGAATGTAGCAAAAGTGAAGAATACCTATAATATTTAATGAAAAT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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