Basic Information
VIS ID
TVIS10020268
Fusion event
HBV-PROX1-AS1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1185
End
2281
Orient
+
Integrated sequence
GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG
Host Sequence
Chromosome
chr1
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
214146399/213973056 (Hg38)
End
214147447/213974104 (Hg38)
Orient
+
Location type
Intronic
Target gene
PROX1-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/1895371; hsa-mir-1182/Downstream/6143749;
Nearest TSS
ENST00000473358/Upstream/46402; ENST00000607726/Downstream/9077;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/583441, chr1-CpG: 42/Downstream/5767
Upstream sequence
CTGTGATATAACTTAGGGGTATGACCAATCAGTCTTCCTGATTTTTCAGTCTGTCTTGACAGTTCTCTCAAAAGCCTCTCTTTTCCCGATCAGCTTCACC
Downstream sequence
GCCCTTGGTAGAAGTGTAAATTAATATTTTTCAAAGAATAAGTGAATAAAGAAATCAGCTCAAGGCAATCTAATATAAACTCTAAATGTGCCCTTTAAGA
Target sequence
AATCTCTCTGCCAAGCACAAAAGGAAGCATTTTCATGTAAGCATTCTGAAATTGGGCATGAGAAGCTGCTGGAATATTTCAGAACATACAGAAGTAGAAAAACTTAACCATATTTATTGAGTATCAGCCAGAAGCACCTGATTATAATAGGCAATGTGGGGAGGGTGGTGACCACAAAAAGTTGGCAGCCTTTGTTCCTGAAGAGAATGTAGTCTAGCCAGCCCACTACCAAAAGGCAATACACACCCATGGAAA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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