Basic Information
VIS ID
TVIS10020272
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1185
End
2281
Orient
+
Integrated sequence
GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
203158442/203189314 (Hg38)
End
203159490/203190362 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-101-1/Upstream/1186078; hsa-mir-1182/Downstream/2257940;
Nearest TSS
ENST00000473358/Upstream/2565; ENST00000433008/Downstream/27659;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/60946, chr1-CpG: 22/Downstream/83029
Nearby gene
CHI3L1(-2520) ;
Upstream sequence
GTCAAAGAAGAAGAAACGCATTGATTGAAATTTATTCTATTACTGAtattttattattaattctcatacaaattcttactagagatatgatttttctcat
Downstream sequence
TATCACGTTTGGTGGAGATCAGCATCATTTTTACAACACATCTTCACTTATCAGCATAGCAAAAATCAGGGATGAAATTGTTTTTTTCGGGGAAtttttt
Target sequence
acggctgggtcattttatccacctttgtatctatccccagtgcttgagacatagtagatgctcagtaaagtactcgttgaataaatgaaCAAATGATCTCAAAATGGTGCATAACTTCACACTCTTATGAGTTTAAACCCTGATGTTCTCAAAATTTCATCTCATTCAATAGTTTTTGTTACCCTGTGAAGAACTGACTCAGGAGGTGCCATAAAACCACAAAACAAGCTTCCTGACTTAATTTCCCTAATCAAA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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