VISDB Viral Integration Site DataBase

VIS ID

TVIS10020273

Fusion event

HBV-SECISBP2L integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1184

End

2280

Orient

+

Integrated sequence

TGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGC

Chromosome

chr15

Cytoband

q21.1

Reference genome

Start

End

49281015/48988818 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-19b-3p ; hsa-mir-21-5p ; hsa-mir-223-3p ; hsa-mir-4520-3p ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-4638-3p ; hsa-mir-4698 ; hsa-mir-3654 ; hsa-mir-409-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-19a-3p ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-33b-5p ; hsa-mir-3143 ; hsa-mir-33a-5p ; hsa-mir-495-5p ; hsa-mir-4803 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-647 ; hsa-mir-6762-3p ; hsa-mir-604 ; hsa-mir-889-5p ; hsa-mir-5197-5p ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-548m ; hsa-mir-1275 ; hsa-mir-1293 ; hsa-mir-1343-5p ; hsa-mir-1468-3p ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-3613-3p ; hsa-mir-376c-3p ; hsa-mir-4259 ; hsa-mir-432-3p ; hsa-mir-4483 ; hsa-mir-4651 ; hsa-mir-4665-5p ; hsa-mir-491-5p ; hsa-mir-541-3p ; hsa-mir-548aj-5p ; hsa-mir-548aw ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-571 ; hsa-mir-6077 ; hsa-mir-608 ; hsa-mir-654-5p ; hsa-mir-6751-5p ; hsa-mir-6752-5p ; hsa-mir-6763-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6803-5p ; hsa-mir-6825-5p ; hsa-mir-6835-5p ; hsa-mir-6842-5p ; hsa-mir-7109-5p ; hsa-mir-7110-5p ; hsa-mir-7-5p ; hsa-mir-92a-2-5p ; hsa-mir-939-5p ; hsa-mir-1243 ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429

Nearest miRNA

hsa-mir-10393/Upstream/3554641; hsa-mir-11181/Downstream/180252;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/11689, chr15-CpG: 43/Downstream/57348

Upstream sequence

tcgaggttgcagtgagctatgatcatgccactgcactctagcctgggtgacagagtaagtctccatcttggaaaacaagaaaGCACTCAGAAGGTGGTGG

Downstream sequence

ATTAAGACATTAAATTATAAACTTATGTGGtatatttagaaattaaattataaaataataCAAATACTTTCAAGGTGTGATGTGCCAACAAAATTTAAAT

Target sequence

AAAGTATTATTATTACATGTAGCTTTTGACTGTTTTCAGGTGCGATGCACACCCTCTTCTGGTTAGGAGAAAAACTGATCACTATTGGAAAAAATTAGGGAGTGGTACATGTACTGGTTAAAAAGGAAGTATCTGATACAACTGATGAGGCATTCTCCTTCGCTTTGTGATCACCAAAAAGTTCATTTCTTTGTTATGAAAATTAGTATCCTATTTTCTGACAGATGAATGCACTTTTTCAGATTCCCTACATTT