Basic Information
VIS ID
TVIS10020274
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1183
End
2279
Orient
+
Integrated sequence
TTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGG
Host Sequence
Chromosome
chr13
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
34584946/34010809 (Hg38)
End
34585994/34011857 (Hg38)
Orient
+
Fragile sites / regions
FRA13A
Nearest miRNA
hsa-mir-2276/Upstream/9848305; hsa-mir-1267/Downstream/5652177;
Nearest TSS
ENST00000623511/Upstream/180057; ENST00000605909/Downstream/336186;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/192453, chr13-CpG: 79/Downstream/930377
Nearby gene
LOC107984589(+6262) ;
Upstream sequence
CTGTCATGCATGTTTTAGAGTGCAGATCATGTGTCTCCTATTAGTCATAAACTACAGGACCTCAGACATACAGAAACATAATTTTCTGTAAAATATATAT
Downstream sequence
gttgctccagcttctgcgcctgcttacctaagtgttctctcctgtgaggggtggaatgtagtgggtctgagtcagtggagtttgatcccgccggcgctga
Target sequence
TTTCACTTTATCATACGCAGGTGTTACTTAAGATTATATAAAATAAAGATAAAGCCCTATCATTACTGGTATTTCGCAAATGAGGAAACAAGTTCCAAGTAGTTTAGTACTTATTTATGAAAGCAAGTGAAATAAATCTTCTTTCAGAGCTCCTTCTAGACTTAGCTTTCAGGCATCTAAATCATAAATCACTATTATTAAAGATCTGTATCAGCAGGGGAAAAACAAATTTTTAGATAATGAACAGTAACACCG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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