Basic Information
VIS ID
TVIS10020279
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1176
End
2272
Orient
+
Integrated sequence
CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC
Host Sequence
Chromosome
chrX
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
86419701/87164698 (Hg38)
End
86420749/87165746 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7f-2/Upstream/1260991; hsa-mir-105-1/Downstream/7897395;
Nearest TSS
ENST00000429181/Upstream/450046; ENST00000373114/Downstream/352003;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1015825, chrX-CpG: 43/Downstream/4268857
Upstream sequence
catttgcttggaataacttttccatctttcgattttcattctttatctgtgtttataggtgacgtgtgtttcttgtaggcaacagatcaagggggtcttg
Downstream sequence
taaatgtcactgtttggtaagcattcacgtgacatacaaatatcttcacatttttcccccattcagagaggttcatccacatacattgtcccagggattc
Target sequence
attgtatctaccctttcactgccaaagataaggacttccttgtcaactaccaaagaacccctggggctctctcacacttagtttttgttttcaatgttatttttattgactttactttgtgttaagagctgtcagctttttattagtcctctgaagaccataaatacagtttaacagcagtcaataaatctctctttctttgtatacattatttcatccatatttttaaaacgTAATACTCTTTATATGTGCGAT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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