Basic Information
VIS ID
TVIS10020280
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1394
End
2490
Orient
+
Integrated sequence
CAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTC
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
137976591/137655454 (Hg38)
End
137977639/137656502 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/2416198; hsa-mir-1202/Downstream/778711;
Nearest TSS
ENST00000381078/Upstream/161204; ENST00000642830/Downstream/1496;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/157219, chr6-CpG: 82/Downstream/210613
Upstream sequence
aggttgtttccatatcttggctgctgtgaatagtgctgcaatgaacacgggggtgcagatatctttacgaggtggtgatttcattcctttggatatatat
Downstream sequence
aaactggtaaaaggcctcagaatttttaagttgtccttaacccgccccccggccccggccttgttttattttgatacatattttctaataatccagtttt
Target sequence
aggagtcaagcttgacttgcagagctgataaaaccccgcaggaaaaactgtcctcatacccttgtctacgcagtccctgtacagggttcctgacctgtgatcagtaaagaatgtcactttctaactggccaaggatctccaagtttatcttgggaccttaagaggaatggatcacccaactcacagttatttgtggatataaaaccatggttgggcttggctttaaaagatatcatctgagattccttgtggaac
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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