Basic Information
VIS ID
TVIS10020281
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1183
End
2279
Orient
+
Integrated sequence
TTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGG
Host Sequence
Chromosome
chr13
Cytoband
q12.11
Reference genome
GRCh37/hg19
Start
22336765/21762626 (Hg38)
End
22337813/21763674 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-4499/Upstream/1328780; hsa-mir-1267/Downstream/2398742;
Nearest TSS
ENST00000623511/Upstream/81513; ENST00000611481/Downstream/111892;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/87010, chr13-CpG: 30/Downstream/932767
Upstream sequence
GACTGGATTAGGGAGGGAGTGAACGGTGGAAGTAGAATTCGGACGAGTAAAAGAGACATGTTTCCCCCTTTTGTATCTCCTTATGTGCTATTTGAATATT
Downstream sequence
ctggagtgcagtggcactatctcggctcactgcaagctccgactcccgggttcacgccattctcccgcctcagcctcccaagtagctgggactgcaggcg
Target sequence
ATTTCTTCATCTGTCAATCTAAAATGAAATGATGAGTAACTTAGGCCAGGTCACTTGGCAGGTGTGGAGGGGAGCGGTGAAGGCAGAAGCCAATTGATACTAAGAATAGGCTTTGTGTTCTCAGCGTTGCCTGGGCCTGTGCTAAATGCATGGAGCGCATCTACCACTATGACAGTCGCTGCCGAAACGATCACCCAGTCGCAGTCACTTTGCTCTGATACACATTTTAAAAATGTTATTGGTGTCAGTGGTAAG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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