Basic Information
VIS ID
TVIS10020283
Fusion event
HBV-LOC105370826 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1184
End
2280
Orient
+
Integrated sequence
TGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGC
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
53681405/53389208 (Hg38)
End
53682453/53390256 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370826
Nearest miRNA
hsa-mir-10393/Upstream/1112008; hsa-mir-11181/Downstream/1982684;
Nearest TSS
ENST00000557528/Upstream/272843; ENST00000561210/Downstream/150824;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/582929, chr15-CpG: 33/Downstream/369202
Upstream sequence
ggtactgcgaaggcggagcagaattctcctcaggtcagacccgggcgggcgggctgagggtaccgcgagggcggagctgcgttctgctcagcacagacct
Downstream sequence
TTCTTTTTGTCTCCAGATATGTTTGAATAGGATTTGAGCACTGAGCTAGGCAGTACCTATGAATGTTTAGCTGTTTTACCATTCATATTCTTAAGAGGCC
Target sequence
AGTGAAGCTGCTAAAAATGGATTCCAGCCTGGGAAAAATTCCCTGGGGAGGCTGTAGATGTCCCGGCCTGGCCTGGCAAGGATGGGTCCTTTGTGACTCAACTGGGTGAGAGCTGAGGGCTGTTCCACCAGTCAAAACCCCAGCCACAATAACCTGGCTCTCGGGTCTCAGATACCTAGCACCTACTGCAGGCTGAGGAGAGAGTGGAAGGAAGAAGCAGGTCCCCCTAGTGTGGACTGGGCTGAGATCGGGTCA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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