Basic Information
VIS ID
TVIS10020285
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1185
End
2281
Orient
+
Integrated sequence
GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
141184928/141805361 (Hg38)
End
141185976/141806409 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10397/Upstream/1157435; hsa-mir-103a-1/Downstream/1873451;
Nearest TSS
ENST00000502646/Upstream/123140; ENST00000506775/Downstream/19916;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/51590, chr5-CpG: 102/Downstream/42956
Nearby gene
LOC107986454(+2437) ;
Upstream sequence
accctagtccatctgagtttaaagcttatccttttactactttccagctgtgtctctgAGGACAGGCACTCAATAGGTGTTCTTGCCCTTGGTTCTATTT
Downstream sequence
TGTTCACGGGTAATGAGCTTGCCCTGCTGCTTTCTGTTCCCTTGACAGTGCCTGGGGCCAGAGATGGGGCTGCCAAGGTGGGAGGCAGGGGCCCCCCACA
Target sequence
tcctcatctgtaaaatgggataagcatgcaacttctctgtgggtatctgaacagaacttctaaaagttctgagcagACATTTGTTGGTATGCAAGGCAATGAGTGGCCTCTGGGAGAAAGTTTAGAGAGGGAAAATGAGAACAGGTTGCTCTTTCTGGTGACCATGGCTCCCTGATGGGGGAAGAGGATTTAAGGACTGACAGGGAGATTGTAAAACCTGAGGGAAAGAGGCAAGAGTGGGAGAGGATCCTGGAA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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