Basic Information
VIS ID
TVIS10020289
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1169
End
2265
Orient
+
Integrated sequence
TCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGT
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
72149437/74482202 (Hg38)
End
72150485/74483250 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1-2/Upstream/1628820;
Nearest TSS
ENST00000575820/Upstream/24258; ENST00000580229/Downstream/12566;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/24720, chr18-CpG: 100/Downstream/12450
Upstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Downstream sequence
AGGGTTTTGGAAAGCCTAACAAGGATGTTTTCACAAATGTAGACAAGACAGCCCCTCTTCTCAGCCACCACCCTCAGCTTGCCACACATGCAGGTTAAAT
Target sequence
AAATAGTGATGATATAAAAAATCGTGAAACAGTAAGTACAACAGAGATGCTTTGGCAGAAATCTACTACGAGTTATTGATTAATGAGTATAATTTTGGGTGAACACATATATATTTTTATTATGTTTTAGTCCCTTTATTTTAAATCTGAAGTAAGCTGCAACAAGTGTTGTATGTTTATAATTAAATCCAGCATTCAGTTCTTTTCTACATAATCCATGCAATACGAGGAGTGAGGACAAGCAAGATTCAACAT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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