VISDB Viral Integration Site DataBase

VIS ID

TVIS10020291

Fusion event

HBV-TRIM44 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1426

End

2522

Orient

+

Integrated sequence

ACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCTTGGACTCTCAGCAAT

Chromosome

chr11

Cytoband

p13

Reference genome

Start

End

35772341/35750793 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-222-3p ; hsa-mir-17-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-4674 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4764-3p ; hsa-mir-3177-5p ; hsa-mir-4417 ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-4437 ; hsa-mir-637 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-545-3p ; hsa-mir-511-3p ; hsa-mir-3908 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-939-5p ; hsa-mir-6883-5p ; hsa-mir-1343-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6827-5p ; hsa-mir-4539 ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-4293 ; hsa-mir-1321 ; hsa-mir-4762-3p ; hsa-mir-3192-3p ; hsa-mir-2115-5p ; hsa-mir-5009-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-4668-3p ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-6826-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-4323 ; hsa-mir-3591-3p ; hsa-mir-21-3p

Nearest miRNA

hsa-mir-1343/Upstream/807825; hsa-let-7a-2/Downstream/259305;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/86391, chr11-CpG: 80/Downstream/193273

Upstream sequence

ATGTGGATTTAGGTCTGTGTCCATCAGGATTTGTCCCCATTCCATTCCTACCCCATCCCACCCAGCATAGATCTTAGGACAGCTTGCCAGCAACAAAGTC

Downstream sequence

CATTTCTCTGCTATTATTCATGTAATTTATTTGTACCGCAATTAAAAGTGTAGCTATCAGGGGTATAGAAAATGAAGGTAATACATATTCCTGGGAAAAG

Target sequence

ATTTTCCAGAGGTTTGACAAACTAATAAGTTAATATTGCCTTTGCAAGGGAAAAAATTAATATCAAAATTTGGGAGCTTGACTGACACAGTAATTATGCTGGAAAATGTAATTTTGCCTCCATAATAGAGATGGGATTATTTCAAGAAGATCTCATTAATGTGCTGTTCATCAACAAATAGGAGTGTAACCTTTCTTTTATTAGATTAATACAGGGTCGTGATGCAAAAGGCTGTTGGAATAATTCTTACTCCTT