Basic Information
VIS ID
TVIS10020293
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1394
End
2490
Orient
+
Integrated sequence
CAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTC
Host Sequence
Chromosome
chr6
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
5831595/5831362 (Hg38)
End
5832643/5832410 (Hg38)
Orient
+
Fragile sites / regions
FRA6B
Nearest miRNA
hsa-mir-3691/Upstream/683040; hsa-mir-10398/Downstream/336894;
Nearest TSS
ENST00000381078/Upstream/136090; ENST00000454882/Downstream/19096;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/569660, chr6-CpG: 29/Downstream/18967
Upstream sequence
GCCATTTGCAGGTCAAGGGATTAGGAACTCAGCTATGGATCAGCCAGAACAGTAGGAGCTGCTACTTTAAGATGTGCCCTAAGCTGGAAGGGCAAACAGC
Downstream sequence
ccccatctcttaaatttaaaaaaaggaagagaaaggagaaggaggaggagcaggagaaggagaaggaggaggaggaggaggagaaggagaaggagaggaa
Target sequence
GCTGCCCAGTCCTGGGCTGGCTGCAGGAGGCTGCTGCATTACCCACCTCAAACCACACAAGCACTGGCAGTAACAAGAGGCCGTAGAGAACCTAGAGTTCTCCAGTGGGTGTGGTTCTCTGGCTGCCGTGGGCTGCCAGGGATCCCTTAGATCACAGACTCCACAGTTCTTTCTTGCCACCTCCAGAAGTGAGGCTGCAGCCCCATGAGCCAGGCAGCAGGAAGGGAGGAAGTCTCGCTTCTTGCCAGACACATT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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