Basic Information
VIS ID
TVIS10020295
Fusion event
HBV-chr9 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1199
End
2295
Orient
+
Integrated sequence
CACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGA
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
106555731/103793450 (Hg38)
End
106556779/103794498 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7a-1/Upstream/5564233; hsa-mir-12126/Downstream/2806430;
Nearest TSS
ENST00000422679/Upstream/363558; ENST00000647310/Downstream/205257;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/2054656, chr9-CpG: 38/Downstream/204851
Upstream sequence
TTGAGCGGAAACTTCCGTCAGGCTTTGAACCAGGCCCTGAACGTTTGCGATGCTAGGGACGCGCCCGTCAACCCGCCGAGCCGCCCTGTGCCTCATGCGG
Downstream sequence
AGGAAAATTACAATAGAAAAATCAGCCGTATGCTGTAGAATGAAATATATTTTGTCATCCACTTTGAACACAGAATCAAATTATTGCTTTAGATGTATAT
Target sequence
TTACCCTTGGGACTTATTCTGTTTATCGTTTTTGTTTTTCTCAAATATTCAGCGATTCTTGATCATCTGTTCATGTTTATAGATGGGAGCAGAGGTTCATCAATATAGCTGGTAGGAATATATTTTCCCAACTTGAATTATAATTCCTGTGCTCCTAACAATCTGTACAGTTTTCATTACAGCGTCTCTGGCTTTGATGATTTTTAAGAATGCTAGAAAGTCCATGTTAGTAATTTTCCTTTGCATATGTTTAAA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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