WWOX _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020296
Fusion event
HBV-WWOX integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1394
End
2490
Orient
+
Integrated sequence
CAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTC
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
79162493/79128596 (Hg38)
End
79163541/79129644 (Hg38)
Orient
+
Location type
Intronic
Target gene
WWOX
Nearest miRNA
hsa-mir-1225/Upstream/2259577; hsa-mir-11401/Downstream/2255374;
Nearest TSS
ENST00000527434/Upstream/50362; ENST00000566103/Downstream/66715;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1028427, chr16-CpG: 44/Downstream/459950
Nearest cancer related gene
WWOX(TSG, No orient, 0)
Upstream sequence
gatgaaagaaattaaagacacatggaaagatatcctaggttcataaattaaaacacttagcatttttcaagtgactatttcaactaaaacaatctaagct
Downstream sequence
CACATTAGTTGCATCCCAACATTCCTTTATGGACTGCATTCCATGCCTGGCACTGTGCCTATGATTTATTAAAATCTAAAGCCATTAATAAATAAATTAT
Target sequence
AGCAAATGCAGTGGCACAGAAGGGTCTGGGCATTTATTTCCAAAGAATGATTTCACTCAACTGAGGAATTCTAATGTTTTAACAGCATCCTACTTATTTCTAAAGTGTTGGGGTGAATTTGCCAAGGTTTGAAAAGTGCATTTGTAAGCCAGTAGGATTCAATCTGAAGTCAGGGATAACAGAGCCGGGGGCGGAGGCTAGGTCTCCTTACATATTTTGTTCACAATGGGACTAGAACACTCTGCAGAGTATGAA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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