Basic Information
VIS ID
TVIS10020298
Fusion event
HBV-LOC101927711 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1185
End
2281
Orient
+
Integrated sequence
GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
GRCh37/hg19
Start
233006950/232871204 (Hg38)
End
233007998/232872252 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
LOC101927711
Nearest miRNA
hsa-mir-101-1/Upstream/1851280; hsa-mir-1537/Downstream/751900;
Nearest TSS
ENST00000473358/Upstream/66312; ENST00000479125/Downstream/78353;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/65243, chr1-CpG: 40/Downstream/78193
Upstream sequence
CGTTATATCAGGATCTTCTTaagatggctgaataggaacaactccggtctgcagcaagatcaacgcagaaggcgggtgatttctgctttccaactgaggt
Downstream sequence
ATTTTCAAGACCTATTCCAGATTGAGCCCAAGGCCTTCCTGGTTCATTCTCAAACTGGGTTTTAGTGAGAGATACCAACATAAAATTGGGGTTGCTTGAC
Target sequence
agtttcgacacacaggttctccaaggccccaccagagcagctagatacagagtgtcaattggtgcattcacaaaccttgagctaaacacagggtgctgattggtgtatttacaatccctgagctagatataaagactctccacgtcctcaccagagtcaggagcccagctggcttcacccagtggatcccgcaccggggctgcaggtggagctgcctgccagtcctgcgccgtgcgctcgcgttcctcagccctt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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