VRK2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020302
Fusion event
HBV-VRK2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1322
End
2418
Orient
+
Integrated sequence
TATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCG
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
58359074/58131939 (Hg38)
End
58360122/58132987 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
VRK2
Nearest miRNA
hsa-mir-1301/Upstream/2131144; hsa-mir-10b/Downstream/2254375;
Nearest TSS
ENST00000437798/Upstream/85064; ENST00000608934/Downstream/32816;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/84652, chr2-CpG: 50/Downstream/107991
Upstream sequence
agctgggattacaggtgcatgccaccacaccttgctaatttttgtatatttagtagagatggggtttcactatgttggccaggctggtcttgaacttctg
Downstream sequence
GGTCAAGTCAAAACACAGTGATGTATAAACAGTTTTTGTATTTAATTTTCCAACTAGTTTACCTAATTAGAATACTGTAATAAAGTAATGATGCTATTTT
Target sequence
CAAGTATTTCATCATGTACTGCACCAGGTCTGAAGGGATACATTAAAGGGAGCTAACAACACAGAGAAGATTGGCATTCACCCAACATGACAACCAAAGCAAATTTCTTTAGTTTGAAAAATATGTTTTAAAAAAACCAAACAACTAACACATAAAATCCATTAAGGTAACATTGTAAAAAGACATGTATTTGAATTACAGTGCAAAATATAAAGTGAAATATCTGTTCTTTTACATGGTATTTCCAAAGCTTAG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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