Basic Information
VIS ID
TVIS10020303
Fusion event
HBV-NBEAP1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1184
End
2280
Orient
+
Integrated sequence
TGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGC
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
20889439/20684110 (Hg38)
End
20890487/20685158 (Hg38)
Orient
+
Location type
Intronic
Target gene
NBEAP1
Nearest miRNA
hsa-mir-10393/Downstream/147637;
Nearest TSS
ENST00000557528/Upstream/40662; ENST00000560839/Downstream/71025;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/101298, chr15-CpG: 76/Downstream/70292
Upstream sequence
CTCTTTGGGGCCTAGAGAGCGGTGGGCTATGAACTTTATCTGACATTCTGAACTAGTTTCCTGTCAATATGCCCATTGAGTGGAAGCCATTGATCAACCA
Downstream sequence
CTGGCCAGAAAGTTTCCTATaaaagcaaaaaatggggatatcagtccatgcagactgactgttccatattttgactaccctcgcctgcttttattcaatc
Target sequence
CACAAATACCTGAGAATATTTATTAACTATGTATAAAAACATAACTAACCTGTTTATAATATACATATATTTATATGCCATTAAAATTTAAATATAGATTTTGACTTATTTTACTATAACTTTATCCATTTCAATTTGTATTTAATTTTTTAAAATAACTAATGTAGATATAACTCATGTAATGTGATCCATGAAGTTTTATTATTTTTGAGGTACTTTTATTATTTAGAATTCAATATATCATAAAGATACACC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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