Basic Information
VIS ID
TVIS10020305
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1322
End
2418
Orient
+
Integrated sequence
TATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCG
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
187192020/186327293 (Hg38)
End
187193068/186328341 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10b/Upstream/1948249; hsa-mir-1244-1/Downstream/1969151;
Nearest TSS
ENST00000437798/Upstream/244060; ENST00000477672/Downstream/28432;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/588110, chr2-CpG: 87/Downstream/157429
Upstream sequence
AAACAAAACCAGAAGGGTGAATCTAGTAATTTAAGATGTCCATATCACTAAATAGAACTATCCATGTAAAAACAGAAATGCACTTAAGACTTCTACTGTG
Downstream sequence
gcaaggagaggaggtgggtcaaatctgtctccccagtttgggatctggggcaagttttaaaggggtcagaggtcaatggaaaggattcaggaatgttagc
Target sequence
tgaatgCAAGAATGCATTTTAGGACTCAAAATAAATTTTGTTTTAAAGACATGTGCCCACTAGAACTTTTCCATTTCATAAATAAGAGGCGAGACTTTGAAACACTAGCTCTGTAATTTGTGTACAGATAGAATATAGAGAGCTCTAGGCAAATAAATGTTCTCACCATTAATGACTTTCTGAGTCACTTTAAATCACTACAAGATTACAGAACTGTACCTAATTCCTATTACTGTGTTTCAAAGAAACACGTTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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