VISDB Viral Integration Site DataBase

VIS ID

TVIS10020306

Fusion event

HBV-CYP2C8 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1363

End

2459

Orient

+

Integrated sequence

CCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCAC

Chromosome

chr10

Cytoband

q23.33

Reference genome

Start

End

96811000/95051243 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-1178-3p ; hsa-mir-6749-5p

Nearest miRNA

hsa-mir-107/Upstream/5457368; hsa-mir-1287/Downstream/1013072;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/504059, chr10-CpG: 63/Downstream/132195

Upstream sequence

TCCATACATCTACCCCAAAGTGTAGTCAGAAGTGTTTGAAATAACCTACTTGTGTGAGTCTTATGCCTAGTAAAATATCTTTAAAGCCATATACAAGTCA

Downstream sequence

agaattgattcagcagaagaaagaattagtgagctttaacacaagctatttgaaaatactgttagaagagacaaaagaaaaaagaataaaaaacaatgaa

Target sequence

aagggaagagtgagaaggactgcattttgtggtttgagtgtcagctcagctgcagtacaatagaacaccaaatagacttctaaggtttttgactctagtccctggcttctgggtggtacctctggacatgcctgggtactggaagaatttgcttcactgaagggaaggacacaggcctggctggattcaccaccaactgattgtagggccccagatccttggaaacataggcagtagccagggaatggttgcagc