Basic Information
VIS ID
TVIS10020310
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1185
End
2281
Orient
+
Integrated sequence
GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
36423/36423 (Hg38)
End
37471/37471 (Hg38)
Orient
+
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-1302-2/Upstream/5920; hsa-mir-101-1/Downstream/150420;
Nearest TSS
ENST00000473358/Upstream/342; ENST00000335137/Downstream/27948;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/6686, chr1-CpG: 30/Downstream/97653
Nearby gene
MIR1302-2(-342) ;
Upstream sequence
aaaggccaaaatagacaaatgggatctaaaccaaagattaaaccaaagagcttctgcacagcaaaagaaactaccatcagagtgaacaggcaacctacag
Downstream sequence
TTCAGGGAGAAGAGAGGAATTAGCAAGGCCAAGCAGAGGCTCCTGAGGGCAGGGCCAAGGGCGGCTTGGTGGGGTGGGGATGGGATGCACAGAGATAACT
Target sequence
TCCTGTAGGTGCTTATTTAACAACGAAATCATCCCGACACAATGAGCCATATGTGAAAAGTCATCCTTCCCCAACACATCCCCCAACAGGCACTCCTCAAGCCTCTCCCACCCAAGTGCTGGCATCCTCCCTGTCCTGCTTCACCTGAGACACCCCTTGTCTCATTAGACATGCAACTACGGGAGGGGTGACAGGAAGACAAGACACTATTTCCTCAGGCCCAGTTTGGTGTGGGGAGAAAGCCTCCTGATCCTG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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