VISDB Viral Integration Site DataBase

VIS ID

TVIS10020311

Fusion event

HBV-FMN2 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1185

End

2281

Orient

+

Integrated sequence

GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG

Chromosome

chr1

Cytoband

q43

Reference genome

Start

End

240369812/240206512 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4738-3p ; hsa-mir-374c-3p ; hsa-mir-4282

Nearest miRNA

hsa-mir-101-1/Upstream/2734273; hsa-mir-3123/Downstream/925760;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/111701, chr1-CpG: 48/Downstream/1047

Upstream sequence

ctcacacatgtaatcccagcactttgggaggcctaggcaggtggatcacgaggtcaggagttcaagaccagcctggccaagatggtgaaaccccgtctct

Downstream sequence

CACTCAGAGCTTTCTTCCCTGTTCTCAGTGGTCTATTTGTCCTCAATGGTATCATTTGAAAATGAGACAGATGTGGACTTAAGATTCTGTGGTAAGTCAC

Target sequence

tttttttttttttttgagacggagtctcgctctgtcacccaggctggagtgcagtggcgcaatctcagctcactgcaagctccgcctcccaggttcatgccattctcctgcctcagcctcctgagtagctgggactacaggcacccgccaccacgcccggctaattttttgtatttttagtagagacggggtttcactgtgttagccaggattgcctcgatctcctgacctcgtgatccacccgcctcggcctcc