Basic Information
VIS ID
TVIS10020313
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1169
End
2265
Orient
+
Integrated sequence
TCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGT
Host Sequence
Chromosome
chr18
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
56108218/58440986 (Hg38)
End
56109266/58442034 (Hg38)
Orient
+
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/2961688; hsa-mir-122/Downstream/9040;
Nearest TSS
ENST00000575820/Upstream/24221; ENST00000590797/Downstream/4241;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/184150, chr18-CpG: 92/Downstream/228945
Nearby gene
LOC107985182(+4805) ;
Upstream sequence
aaaaaaaaTAATAATACTTAATTAAAAATAAAACAGGGAAATTGAAACCATCATCTCTTAACTGCCTTTACTTGCAGAAGAATAAACCACCTTGGCTTAG
Downstream sequence
aacctggaggaagaggttgcgatgagccaagatcgcgccactgcactccagcctaggtgacagagcgagactctgtctcaaggcaaaaaaagaaagaaaa
Target sequence
AAATTAAATTCCTTCATTTTCAAACAAATAATTTTCCCCACGTTTTAACATCTCTATAATCTGCATacgggttttcaccatgttagccaggctggtctcaaaatcctgaccacaaatgatctgcccatctcagcctcccaaagtgctgggattataggcatgagccaccgcgcctggccAGTTTACTCTTTAACCTTCTCTCCTTTCTTCTCAAATCCTCCTTCCATGGGGCGTTGCTTAATCACACTATCTGGA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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