Basic Information
VIS ID
TVIS10020315
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1185
End
2281
Orient
+
Integrated sequence
GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG
Host Sequence
Chromosome
chr5
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
126967359/127631667 (Hg38)
End
126968407/127632715 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10397/Upstream/8476951; hsa-mir-103a-1/Downstream/1464973;
Nearest TSS
ENST00000502646/Upstream/40957; ENST00000514851/Downstream/16329;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/113434, chr5-CpG: 200/Downstream/450187
Upstream sequence
aatcagcactctgtatctagctcaaggtttgtaaacataccaatcagcaccctgtgtctagctcagggtttgtgaatgcaccaatcgacactctgtatct
Downstream sequence
tctatggctgttttcatactgtaacagagttaagtggtaagtaccaagaccaagtggcctgcaaatcactttacaggaaaaatttgctggctcttgAATT
Target sequence
GTGTGATTTTTTTTAAGTATGTAAATCTGAAAGTGAAATGATTTGGTTTTATACCTTGGAGCTCTACTAGGGATCTCACTATCCATTTAGAAATGATGTGTCCGTGGTGATGAGGATACAGCAAGTAGGAAACTTTCTGAACTGGTAGTGAGCCCATATCTCTCCTGGGCACCAGAGAAACTCAGTACAAGTTATCAGTAGACTTCAGTGTGGTTAAAGCTGTCCAACTGGGGCCCAGCAGCACCCTGCAACTCT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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