VISDB Viral Integration Site DataBase

VIS ID

TVIS10020318

Fusion event

HBV-TRDN integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1394

End

2490

Orient

+

Integrated sequence

CAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTC

Chromosome

chr6

Cytoband

q22.31

Reference genome

Start

End

123612282/123291137 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-561-5p ; hsa-mir-4761-5p ; hsa-mir-3974 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-491-3p ; hsa-mir-7703 ; hsa-mir-6845-3p ; hsa-mir-4639-3p ; hsa-mir-502-3p ; hsa-mir-501-3p

Nearest miRNA

hsa-mir-10398/Upstream/3274832; hsa-mir-1202/Downstream/3193494;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/293481, chr6-CpG: 98/Downstream/511895

Upstream sequence

tggctaggaacaagataaatattctcaagtatatgaaaggctatcatgtaaaaatagaagagccttcttctgttcgtcccaaaggcataactacagcaag

Downstream sequence

tggagtgagactctgtcaaaaaaaatgtattttcttttccaagaaagcatataataaaagagtaattttatatgaagagggatcttgtatagtcatattt

Target sequence

ccactactgggtgagctctctggtgccttagggactccgggatagtcccttgagtaatgcagttcactccttcccttctttatttgatgctatggaatccccttccctgtctctttctattttccacacctattgaggcaaacaaaatttagtcaggcagctgggtcccaattttgtaaataacttgaatccagttgtcttgtataggtcattttatctagtgtgtttctttagctctatctacaggcattgtga