Basic Information
VIS ID
TVIS10020319
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1260
End
2356
Orient
+
Integrated sequence
CCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCG
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
195165505/195444776 (Hg38)
End
195166553/195445824 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7g/Upstream/310196; hsa-mir-4797/Downstream/253577;
Nearest TSS
ENST00000440867/Upstream/1698; ENST00000426109/Downstream/73815;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1386, chr3-CpG: 94/Downstream/96906
Nearby gene
ACAP2(-1600) ;
Upstream sequence
TTGAGAATATTCTAACAGAACTTTGACACAGGCACTTGAGAAATTTCTGCAGATTATATCTTAAAGAGCAATAATGCAATTTTGGTGAAAAATAAAGAGG
Downstream sequence
CCCGTGTAGCAATCTCCCTTTCATCTTCTCTTTAAAACACCACTCTTATGCCACCCCCTCAGGAAGCTTTCTTGGCCGAAATACAAACCTCTCTATTCAA
Target sequence
tcaagactgcagtgagccatgattgtgccactgcactccagcctgggtagacagagcaaaacactgtatcaaaagaaaaaaaaaggaaaaaggaaaattaacagtataattctgaggcatttcagagaatatagaagcattatattcatttattctttgcttataaacttgatttcttttttaattgtgtattcctggaaaccacacagcttttcttgatagctaaaaacagactattgactgttaaatgttcag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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