Basic Information
VIS ID
TVIS10020320
Fusion event
HBV-LOC105374039 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1260
End
2356
Orient
+
Integrated sequence
CCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCG
Host Sequence
Chromosome
chr3
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
111198366/111479519 (Hg38)
End
111199414/111480567 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374039
Nearest miRNA
hsa-let-7g/Upstream/1876622; hsa-mir-12124/Downstream/632234;
Nearest TSS
ENST00000440867/Upstream/186800; ENST00000488054/Downstream/16528;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/406965, chr3-CpG: 21/Downstream/193913
Upstream sequence
agtgaacacaccaaatgaggtccctgctcttacaaagcttacatctggtggagattgaggggtggaggctaggacattcaataaaaactagctgtatgaa
Downstream sequence
ATATAGAGCAGAAGATGGCCAGAGACTAGCTACTAGTCTTACTTAGTCACTCTTCATTGATCAATTGTATCATTAGTTGATGCattcattcattcaccca
Target sequence
CAGTTGTGTGTACATAAATGTGTATATGTGCTTATGGCTGTGTGTACAAAATATACCTTTATAAAACCACACATTTCCCCAGCACTCCAAAGAGAATCAGTGTCCAATTTAATTGCTGTCCTAGATGTGTGTTCTCTCAACAACTGTCTGGAAATGGTAACCATGACACGTTACTGCTCCACATTAATGGTAATCTGTCTACTGGCTTTTTTGATCAGTCTAATtgttaccggaaaggggtcccaatctagaccc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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