VISDB Viral Integration Site DataBase

VIS ID

TVIS10020321

Fusion event

HBV-chr13 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1183

End

2279

Orient

+

Integrated sequence

TTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGG

Chromosome

chr13

Cytoband

q14.11

Reference genome

Start

End

41381811/40807675 (Hg38)

Orient

+

Location type

Intronic

Target gene

SLC25A15 ; TPTE2P5

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-375 ; hsa-mir-7-5p ; hsa-mir-24-3p ; hsa-mir-423-3p ; hsa-mir-218-5p ; hsa-mir-6807-5p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6720-3p ; hsa-mir-668-5p ; hsa-mir-4252 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-1273g-3p ; hsa-mir-1295b-3p ; hsa-mir-3186-5p ; hsa-mir-1227-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4722-3p ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6727-3p ; hsa-mir-6747-3p

Nearest miRNA

hsa-mir-2276/Upstream/78740; hsa-mir-1267/Downstream/3091;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/16444, chr13-CpG: 43/Downstream/113965

Upstream sequence

TAGGTGGTCACTTGCCAGCTCTGAGATTGTGAAAATACTAAGGGGGATTTGGAATTTGGGAGGCTTTATTAAACAAGGATTTGGACTAGAAATGGACAAG

Downstream sequence

GAAGCAGTACATCCCAAACTTTCTTACTGGAATAAAGTTTTTTAATTTTTCTGGATCTATTTTAGGGGAGAAGAAATCCAGAAATTACTTTCCCAATTGG

Target sequence

CCTTGGGACTTGATCCTTcatctgtccaagccaagtctccttcttgctgagaacaaagtgaggagagagggattcactaagttgcactgagtatgtgatttcttGGCCTGTTCTTAGCAGGGATAAACCTGCCCTGGTTGCCCTCAATCATGAAGGGGAGTCAGACAAAGAGTGTCCTGTGTTCTGGCTGCTACAGGAGCAGGGCTGCTTAGAAGAAATTCTCCCGCATCCCTGGTGCTCTGAGAAATAAATTCT