Basic Information
VIS ID
TVIS10020324
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1192
End
2288
Orient
+
Integrated sequence
CAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATC
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
150316132/150619044 (Hg38)
End
150317180/150620092 (Hg38)
Orient
+
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/3240923; hsa-mir-153-2/Downstream/618329;
Nearest TSS
ENST00000635602/Upstream/51608; ENST00000487388/Downstream/12254;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/210602, chr7-CpG: 44/Downstream/100234
Nearby gene
LOC100288724(-4224) ; GIMAP6(+6331) ;
Upstream sequence
TCCCTTGAAAGAAAAGAAGAAAAAAAACAAAACCAGCATGAAAGTGTTTTTGGATTTGCTCTTCATCTTCCTTTGACATCTTTCTAAGTTGAGGTCTTTC
Downstream sequence
TGATGAGGTTCAGATGGAAAAGACAAGAGATCAAAGAGGTTAGTAGGTTCAGAATAGTTTTCTATTAGCACACTGCAAAGATTTCCTTAAAGGGCAATTT
Target sequence
gcaatggcacacattgaactgccatcgtctgtgataacaatgacttattctggaatagctcctgaagaacctgcctgaggggctatttacaattaactttttttataagtagaaggagtatactctaaaacaatgatttaaaatatagtaaatacataaaccagtaacatagtcatttattattacaatcaagtattatgtactgtaaataattgtatgttctatatgactggcagcttttcacaccaatgtcac
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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