Basic Information
VIS ID
TVIS10020330
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1401
End
2497
Orient
+
Integrated sequence
ATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACA
Host Sequence
Chromosome
chr4
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
15420561/15418937 (Hg38)
End
15421609/15419985 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
C1QTNF7 ; LOC101929095
Nearest miRNA
hsa-mir-12113/Upstream/1790980; hsa-mir-12115/Downstream/5108290;
Nearest TSS
ENST00000502981/Upstream/44386; ENST00000444304/Downstream/47;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/413800, chr4-CpG: 145/Downstream/234756
Upstream sequence
ttctgcttgctttaggctttaactgctcttctctctctgtttcctgaggttgaaacttagattattggctttagagctttcttcttttctaatgtatgca
Downstream sequence
agtccaagaaatctatctattaataggagtcacatacgattctcatcactggcaaactcttcactggcttcttaatgccctgaagataaagtctaagttc
Target sequence
CACAAAAATGGCACAAATGCCAATACCATTGTGGAACAAGCTTTGACGTTCTCTTCACAGCAgaggttagcttcactaacctttaaagttacttccaaatctgagattctgtggctccgtcTGTGTTCCAGGGACAAAAGGTGCCTGGCTGTGGGGGAACTTACATTCCCCAGGATTTTGTTTTTATACAGGGACAAggcagtgtaaattcacacaaccttttggaaagcagtttggcagcatgtaccaaaaaag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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