Basic Information
VIS ID
TVIS10020331
Fusion event
HBV-LOC105379107 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1185
End
2281
Orient
+
Integrated sequence
GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG
Host Sequence
Chromosome
chr5
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
103252718/103917017 (Hg38)
End
103253766/103918065 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
LOC105379107
Nearest miRNA
hsa-mir-10397/Upstream/3100452; hsa-mir-103a-1/Downstream/6595764;
Nearest TSS
ENST00000502646/Upstream/354224; ENST00000514769/Downstream/161846;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/657168, chr5-CpG: 253/Downstream/3751364
Upstream sequence
TGTATTTTTGTTTGTTTTTCACAATCTGCCTCTTTTCCAAGAAATTCTCCATAAAATCTATTTTCATACATCAAGAATCCTTAGTTCATATATTTTTGAG
Downstream sequence
TTTAATGGCTATATTTGAATTTTACATTGCaaaataattttatgataaatataaattaGGTGAAGAACAAGTAAATTTCCATGTAGAGCAAATTGTATGT
Target sequence
ATATGTAAATAAGAGAAAATTGCTAAGAATATAGTTTTGTTATAGCTTAAACACTTTCTGCTGGCCAAGCCGCTTTTATTTCACATAGGTCTCTATCTTCTGTACACTCTGGTTGAGAAAACTGGAACTACATATAGTTTTGCTTCCAACAGTTGTTTTGACAGAAATTTTCAAAAGCTGTGTGTTCTTTGCGAAACACAGCTTCCACAATTTGTTTCTGTCTGCCATCTTGTTCAAAACTATATCCCCTCCCCC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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