Basic Information
VIS ID
TVIS10020332
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1394
End
2490
Orient
+
Integrated sequence
CAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTC
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
78283293/77573576 (Hg38)
End
78284341/77574624 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/2145103; hsa-mir-10524/Downstream/964639;
Nearest TSS
ENST00000381078/Upstream/109803; ENST00000602452/Downstream/116034;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/109201, chr6-CpG: 36/Downstream/75516
Upstream sequence
TGGTGAACAGTAGTAAATGCAGCACGTGGGTATATGTAGTGTAGAATGACTGTCTCTGTGCCATGCATGGGTGTGGGGTGTCCTTTGACGTGATTTTGGT
Downstream sequence
accaatataactatttaaggtaagattgcattgaaatggagtaatctattaatccaatatgactgctattcttataaggagatgacatgaagacaaagaa
Target sequence
ccatatttccaggtgttagcattttccttctgcatgaaggatgaattttaacatttcttgtagtgcactgctatctgcAAtcatttcaggtgttcttttctccagccttcaatagtttcttcacacatatgagctgatcagtattcagctgaatactcaagggggatgtgtgcagattttcagggttttctcttcattcagctctctcctcttcagtattctttcctgtaaactccagccatatttgtctcccca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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