Basic Information
VIS ID
TVIS10020333
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1394
End
2490
Orient
+
Integrated sequence
CAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTC
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
88623586/87913868 (Hg38)
End
88624634/87914916 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/9374559; hsa-mir-1202/Downstream/2397826;
Nearest TSS
ENST00000381078/Upstream/211659; ENST00000237201/Downstream/132873;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/211418, chr6-CpG: 76/Downstream/132658
Nearby gene
LOC101928911(-2137) ;
Upstream sequence
gagtatttctccattccatgtgcctggctttgacctctggaataagtggacatggcagtgggctagttctatgcctggtactgcaggggctttgcaagtg
Downstream sequence
TTCTCCAATGCTGACATGTAAGTGATTTTTCTTCCTGTCATTCGGCTTGTATACATGTTTGCATTTTCCTCTGGAAAAGGAATGCTGGTTTCCATCATAG
Target sequence
TTACTGGGTTTTCTTGGCCTCCTGGCTGAGTGACCTGTTTATTTTTATGAATAAAACTTCATATTCGTTGCAAAAGTATAACAACAACACTGAATAATAGTATACTATAAGACTGTGTTGTCTAAGGATACCAGTGCTCAGCTCAGGCTTCTGTTTTTCTGATATCGAGTAGCAAAATGCACCCTCTCCTTTTTGCCCCCTTCTCCCATGGTAGTGAATGAGCTTTGAAACCTTTTTGATTCTGAATGAGCAGCA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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