VISDB Viral Integration Site DataBase

VIS ID

TVIS10020335

Fusion event

HBV-TEX10 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1199

End

2295

Orient

+

Integrated sequence

CACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGA

Chromosome

chr9

Cytoband

q31.1

Reference genome

Start

End

103074774/100312492 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-222-3p ; hsa-mir-92a-3p

Nearest miRNA

hsa-let-7a-1/Upstream/2082227; hsa-mir-12126/Downstream/6288436;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/212049, chr9-CpG: 93/Downstream/39821

Upstream sequence

caacactttgggaggccaaggcaggtggatcacttgagcctagttcgagaccagcctgggcaacatggcaaaatcctgtgtctgcaaaacatacaaaaag

Downstream sequence

tgtggtgttgaatGACTACTTTAtgtccaataagaggatacgggagaagcaacatccaacagcaataagcacacctaaattccacatgttggtttctaaa

Target sequence

gtttcctaaagaacctactgaggatattaagtgagggcatactgTATTTCTATTGAGTGCTATGACAGAAAGATCTGAGTGATATGAACAAAGGGCTAACAAAAGCTTTTTTTTGCCCACCTGATAGAGAAATGTATCACAGAAAAATATTTATGACCCAGAAAATACAAATATCCTGTTCAATTTAATCATAACACTGCCTTCTCTAAAGGTAAAAAAGAAATCTGCACAAAAAGTAGAGAGTTAGAAGTAAAA