Basic Information
VIS ID
TVIS10020340
Fusion event
HBV-chr20 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1137
End
2233
Orient
+
Integrated sequence
AACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCT
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
10317202/10336554 (Hg38)
End
10318250/10337602 (Hg38)
Orient
+
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/2964862; hsa-mir-1-1/Downstream/312034;
Nearest TSS
ENST00000382410/Upstream/40324; ENST00000334534/Downstream/31117;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/118218, chr20-CpG: 71/Downstream/96026
Nearby gene
HIGD1AP15(-1336) ;
Upstream sequence
TGATTCGAGGAGAGAGCCATTCTGCTCTGCTTACTAGCTGCCTGTCTGcatctggggacacttacaaacctttgatgcctgtttactcccctactcgcca
Downstream sequence
atggccttttgtgtctggctcttctgaggcagcataatgttttccaggctcatccatactatagcatgaatgaacactcatccatttttatggcttaggg
Target sequence
TCACCCTCTCCATTTCTTCCTAAGGGTAAAAGAAATAGTATTTGTTTGGTTTGTTTATCAGGGTATCGTTGTGGAAGGAGAGAAGACTTGAAGAATTGAGAAGGTGCAATTAATCTTCATGAGAACAAAAAGAGAAAAGACAGGAGAAACAGAAGAGCTAGCACAACTGGAAACTTTGGAGAGTACGTGAGAGAGAAAAGATTCAGGAAGAGCTATTAGGAGTGGAATATTTCGGGGGGATGGTATATAAGAAGG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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