VISDB Viral Integration Site DataBase

VIS ID

TVIS10020342

Fusion event

HBV-ZNF331 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1185

End

2281

Orient

+

Integrated sequence

GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG

Chromosome

chr19

Cytoband

q13.42

Reference genome

Start

End

54071663/53568409 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-4474-3p ; hsa-mir-7108-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-6815-3p ; hsa-mir-5696 ; hsa-mir-6828-5p ; hsa-mir-4729 ; hsa-mir-6510-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-31-5p ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-5586-3p ; hsa-mir-508-5p

Nearest miRNA

hsa-let-7e/Upstream/1285468; hsa-mir-10394/Downstream/98270;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/12361, chr19-CpG: 86/Downstream/79413

Upstream sequence

gccaagatcacgccattgcactctaacctgggcaacaagagcaaaactccgtctcaaaaaataaactaattaattacaaataaataaataaataaaaata

Downstream sequence

ttggaagtttttattggggcctcagcatgtagacatgattgactggttggtggattaactgtctacatggttaatcttagtgtccaggtcagctgatact

Target sequence

GGAGGGGCCAGGGTAGGCTCAGAATGAGACTGAATACTCTGAGCACCCACTGTCTGATCCTAGATCACAATCCCCCCATCCagagttagctaatctatgaggctcatgggtatggtctgcatagaagaccaccctcacttctgacaccactgcaagcttggtggggattcctcaaaccgccctcaggttcaacagttcactagagccaggcatggtgactcatgcctataatcccagcaccttgggaagctaagg