VISDB Viral Integration Site DataBase

VIS ID

TVIS10020345

Fusion event

HBV-KCNAB1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1260

End

2356

Orient

+

Integrated sequence

CCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCG

Chromosome

chr3

Cytoband

q25.31

Reference genome

Start

End

156017213/156299424 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-144-5p ; hsa-mir-3613-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-4282 ; hsa-mir-3606-3p

Nearest miRNA

hsa-let-7g/Upstream/4732381; hsa-mir-1224/Downstream/2983222;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/6845, chr3-CpG: 49/Downstream/255423

Upstream sequence

atatctccaaactcattctaccaggctagtattaccctgataccaagccatgcaaagacacattacaacaacagcaacagcaacaaataaacagacaaaa

Downstream sequence

TAACTTCCAGATGATAGCATGCTTAGCATCACAGTGTCTAAAGCACAGGCTTCTCAGGAAGAGATCTACAAAACCATAGGCATATATGATTGAACATTGC

Target sequence

TTGTTACACATGGAGTCCTTAATCCCACATCCACTCAATGACCCTCTTTAGAAGTACACTCATTTTAAAGAAATTCTTTTTTAAAAATTCTGCAAACATTTCAATTTATGGTAATTTGAGAAATGTTCTGAAAGGAGAAAAAAATCCCATCACATTCAAAAGGAAAATCAGATTCCTAAATTTCACTTTGATTTTTAAAATTCCTTTCATCAAATTCATAGTCTATCTTTAGTATATCAATTTATGAACAGTATG