VISDB Viral Integration Site DataBase

VIS ID

TVIS10020349

Fusion event

HBV-MPHOSPH8 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1183

End

2279

Orient

+

Integrated sequence

TTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGG

Chromosome

chr13

Cytoband

q12.11

Reference genome

Start

End

20224694/19650554 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-20a-5p ; hsa-mir-545-3p ; hsa-mir-216b-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-1273e ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4327 ; hsa-mir-6499-3p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-4695-5p ; hsa-mir-34b-3p ; hsa-mir-4503 ; hsa-mir-6792-5p ; hsa-mir-7856-5p

Nearest miRNA

hsa-mir-1267/Downstream/783224;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/15580, chr13-CpG: 116/Downstream/131453

Upstream sequence

ccttttcattgtctgtttagtgtcatgtcttttgtttttgtttttgcctgtatttctgcactttttgatggtgattttgttgtttaaaatggcctcaagc

Downstream sequence

TTTAATAGATTTCTTTCAGGAAATTATCAAATATAAACTTATTTGTATTTTACCCTTTTAATGTTGTAGCAAGTAACACTAAATAAGATTATATTATAAA

Target sequence

GTTTTCTTCCCACTTTCTTCTTTAGTTAAAAGCTGGTAGCGTCAGGTACAGTTTTACCAGGTACACAGGCAGTGCTCTGGCACCCTGCTGTTTCCCTCACTTGCCACCAGAAGCCATTTTGGTACAAGCTTCAACATCCAGCTATAGACAGTCTGGTGTCTTTAGCTGTGGGAAAGGTGCTGGTGTGACTTGGATCACTCTGAGACTCACTGCCTTCAGTAGGCCTTTGTCACAACTGCAGGTGAGTAGTTCAGA