VISDB Viral Integration Site DataBase

VIS ID

TVIS10020352

Fusion event

HBV-NID1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1185

End

2281

Orient

+

Integrated sequence

GCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCG

Chromosome

chr1

Cytoband

q42.3

Reference genome

Start

End

236140405/235977105 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-29b-3p ; hsa-mir-106b-5p ; hsa-mir-186-5p ; hsa-mir-6760-5p ; hsa-mir-423-5p ; hsa-mir-3151-5p ; hsa-mir-92a-2-5p ; hsa-mir-486-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-6770-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-6856-5p ; hsa-mir-4768-3p ; hsa-mir-6758-5p ; hsa-mir-192-5p ; hsa-mir-215-5p

Nearest miRNA

hsa-mir-101-1/Upstream/122997; hsa-mir-3123/Downstream/1494014;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/108760, chr1-CpG: 37/Downstream/16468

Upstream sequence

aagtggaaatttcaaaatagctaaaagagtgttttttgcatgtccagcaactggtgaataaacaaaatgtggtTTAAAAAAAAAAAAAAAAAGAATTGTC

Downstream sequence

TACACCTTGAAATTCCTACCATTGGACATTCTTTTGATTTAAGCCTTTAACTAACAAATGCCAATATCCTACTGCTCAAATATTGACATTCTATCTGGGA

Target sequence

ATATGAAACGATAAATACAAAAAGTGAGACTAATTTATGGATTTGGGCTACGTAAAAGACCTACATGGTCCTCGAATCTTGTGATTCTTGGGGCTATATTTGCCTCTCAAGACAAACTCCAATTATTCAAGGAAGACTTTCTTTCAATTCAGGTTCCAATGTACTGCAGAAGCAAGTGAGGACAAAGTCAGGAGAAGGTGGGGCAGAGAGGCTGAGTGTACTGGGGTTTGAGGAAAAGAGGAGAGACTCTTTTCC