VISDB Viral Integration Site DataBase

VIS ID

TVIS10020357

Fusion event

HBV-FRZB integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1

End

915

Orient

+

Integrated sequence

TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG

Chromosome

chr2

Cytoband

q32.1

Reference genome

Start

End

183703734/182839006 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-30b-5p ; hsa-mir-744-5p ; hsa-mir-451a ; hsa-mir-125b-1-3p

Nearest miRNA

hsa-mir-10b/Upstream/1532306; hsa-mir-1244-1/Downstream/1539969;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/121483, chr2-CpG: 38/Downstream/27074

Upstream sequence

GGTATTACTGATTAATTGAATTACCACATTTATAGCAGCATGTAAATCACATCTTCTTGCTTATTCCCTTTTAAAGAGCGCTATCTTGAACAGAAAGGGG

Downstream sequence

TATGTTAATTTTACTATATGAAAAGACCTAATACTTAAATATGCTTTATTCCTTGTCGACACTGTTTTATCAGGTCCATTAACAGGTTTTCTCAAGTAGT

Target sequence

TACCGAGTCGATCCTTCCACTTCTCAGCTATAGAGCCTTCCACCAAGAGTAATCTGTATTTTTGAAAGAAGCAAACATTTTTGAAAAATTAAAACCTGTTACTGAAAAGTACAAGGAAACAGTACTTGAACAAGAAAGACTTATATGTTTATTCTTGAATAGGACAGCTAAGATTTAGAAcagtaattattaaccatttgtaagtcacagacccctttaagaaacaaatgaagttatggcccctctcccaagaaa