VISDB Viral Integration Site DataBase

VIS ID

TVIS10020358

Fusion event

HBV-FN1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1

End

915

Orient

+

Integrated sequence

TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216247456/215382733 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1623526; hsa-mir-1244-1/Downstream/2517780;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/69276, chr2-CpG: 43/Downstream/52811

Upstream sequence

ATACAAGTTTAGTGGTATAGAAGATAAAGGACACTAAGGAATTGTGTAACAAAATGACTTCTTGGTTCCCTACAGCTGTTAAGTATGAAAACACACCATG

Downstream sequence

GATAAACAAAACCAGAAGGGTGAATCTAGTAATTTAAGATGTCCATATCACTAAATAGAACTATCCATGTAAAAACAGAAATGCACTTAAGACTTCTACT

Target sequence

ctggtctcgaactcctgacctcgtgatccgcctgcctcagcctcccaaaatgctgggattacaggcgtgagccCAGCCCTATAATGGTTCTTACACTCTTCTTTTCCCCTCTCTATTAAGCATTTATATTACACTCTGGTCCAGCCATAGCCCTTCAAATGCCCCAAACATAAAGCTACATGAGGCACACTTCAATCAACTTTACCATCCAGTTGTAGAAAAGACGGTCTAGGAAAATTTTTTGTAGATTTGCTA